The "Proportional Bactericidal Test": A Method for Assessing Bactericidal Activity of Drugs AgainsMycobacterium lepraein Mice
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The early bactericidal activity of antituberculosis drugs.
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متن کاملBactericidal Activity
as frequent in those with bactericidal activity (54%) as in those without (56%). The coexistence of bactericidal activity and bacteremia was reproduced and studied in experimentally infected weanling rats. Serum from such rats kills in vitro 95% of conventionally broth-grown bacteria within 10 min, but does not kill organisms obtained from the infected animals. Thus bactericidal activity as con...
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The serum bactericidal test represents one of the few in vitro tests performed in the clinical microbiology laboratory that combines the interaction of the pathogen, the antimicrobial agent, and the patient. Although the use of such a test antedates the antimicrobial era, its performance, results, and interpretation have been subject to question and controversy. Much of the confusion concerning...
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Bactericidal antibody is required for direct complement-mediated killing of most pathogenic gram-negative bacteria. Although it has been implicitly assumed that bactericidal antibody functions by increasing complement activation and deposition on the bacterial surface, this assumption may not be valid. We have shown previously (1) that bactericidal IgG increases the bactericidal efficiency of C...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 1978
ISSN: 0305-7518
DOI: 10.5935/0305-7518.19780002